For the first phase of the SG10K project, researchers sequenced thousands of Chinese, Malay, or Indian individuals from Singapore, uncovering new variants and population insights.
An analysis of more than 900 C. difficile isolates uncovered four phylogenetic lineages, including three lineages in a clade showing recent positive selection on infection-related genes.
Researchers analyzed more than 550 new and previously sequenced exomes for individuals from African rainforest hunter-gatherer and farming populations, searching for local adaptations.
Based on sequences for hundreds of E. coli ST131 lineage isolates, researchers propose a model that involves negative frequency-dependent selection on accessory parts of the genome.
Using meat and clinical samples collected prospectively over a year, researchers found evidence for poultry-to-human transmission of Escherichia coli sequence type 131.
By sequencing four ancient cave bears and comparing them to other bear species, researchers retraced historical admixture of cave bears and brown bears.
Diet- and height-related variants were selected for in a Flores Island pygmy population, according to a study, which also provided insights into the population's history.
When researchers sequenced some 800 global Staphylococcus aureus isolates, they saw signs of previous jumps from humans to domestic animals and beyond.
Using genome sequencing and phylogenetics, researchers have shown that the industrial yeast Pichia kudriavzevii is genetically the same species as Candida krusei.
In Science this week: approach to measure microRNA targeting efficiency, strategy to conduct high-throughput chemical screens at single-cell resolution, and more.
