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adaptation

Using sequence data from nearly 2,500 isolates submitted to GISAID before April, researchers tallied coding and non-coding changes in the virus across locations and conditions.

Ebola viruses passaged in bat renal cells appeared to be subject to RNA editing by host enzymes, while more adaptive mutations arose after passaging in a human kidney cell line.

The genomes of modern sled dogs, an ancient Siberian dog, and an ancient wolf revealed genetic similarity between the ancient dog and modern sled dogs.

Northern and southern Italians further developed what appear to be genetic adaptations affecting susceptibility to obesity and melanoma, respectively.

By sequencing ancient Salmonella enterica isolates, investigators retraced the history of the bug in humans transitioning to pastoral and agricultural lifestyles.

For the first phase of the SG10K project, researchers sequenced thousands of Chinese, Malay, or Indian individuals from Singapore, uncovering new variants and population insights.

An analysis of more than 900 C. difficile isolates uncovered four phylogenetic lineages, including three lineages in a clade showing recent positive selection on infection-related genes.

Researchers analyzed more than 550 new and previously sequenced exomes for individuals from African rainforest hunter-gatherer and farming populations, searching for local adaptations.

Based on sequences for hundreds of E. coli ST131 lineage isolates, researchers propose a model that involves negative frequency-dependent selection on accessory parts of the genome.

Using meat and clinical samples collected prospectively over a year, researchers found evidence for poultry-to-human transmission of Escherichia coli sequence type 131.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.