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The Scan

New research, and a burgeoning company, point to the possible benefits of deep data profiling on healthy individuals, but critics aren't convinced.

This Week in Nature

In Nature this week: a next-generation characterization of the Cancer Cell Line Encyclopedia, and more.

Unreproducible?

A report from the National Academies says researchers, academic institutions, journals, and funders need to take steps to improve reproducibility and replicability in science.

See You in Court!

US laws are falling behind the rapid progress of genetic testing technologies, and the lawsuits are starting to pile up, Science Magazine says.

Agreement Made

The NIH has reached an agreement with the Navajo Nation to allow researchers to access health data from tribe members, Nature News reports.

In Nucleic Acids Research this week: a pipeline for developing multi-locus sequence analysis-based bacterial trees, a chromatin state sequence comparison tool, and more.

Business Insider reports that uBiome halted the sale and testing of its SmartJane and SmartGut tests.

At the BMJ, David Shaw from the University of Basel and Maastricht University critiques the National Health Service's clinical sequencing plan.

Reuters reports that on the launch of Verve Therapeutics, a biotech focused on using gene editing to treat cardiovascular disease.

This Week in PNAS

In PNAS this week: sequencing of Globular Amphora culture individuals, characterization of effects of variants of unknown significance in EGFR, and more.

And, Speak

The Wall Street Journal reports that the US National Institutes of Health is to allow two clinicians critical of a clinical trial to speak with investigators.

Researchers tie genetic variants to traits linked to exercise-associated collapse among athletes with sickle cell trait, New Scientist reports.

But Useful?

Researchers question the value of a predictive genetic test for obesity, NPR reports.

This Week in PLOS

In PLOS this week: exome sequencing ties PIK3C2A mutation to new Mendelian disorder, genetic profiles of Plasmodium species in Namibia, and more.

Wired reports that "organs on a chip" are among the cargo to be delivered to the International Space Station.

NPR writes that, despite concerns, researchers don't know enough about genetics to make "designer babies."

With CRISPR being applied to a range of biological problems, researchers are searching for ways to stop its edits, Technology Review reports.

This Week in Science

In Science this week: gene variants in Gulf killifish adapted to polluted regions, and more.

US officials are to pilot a DNA testing program aimed at catching migrants traveling with children who are not their own, Time reports.

Plus, They Look Cool

Narwhals are doing well despite their low levels of genetic diversity, according to a new iScience study.

CNN reports that an experimental treatment is showing promise for treating the genetic form of amyotrophic lateral sclerosis.

This Week in Nature

In Nature this week: resequencing hundreds of chickpea varieties gives peek into its domestication, and more.

In an initial vote, the US National Academy of Sciences approved an amendment to allow the expulsion of members who violate its code of conduct, according to the Verge.

New Scientist reports that songbirds have an extra chromosome within their germline, but not other, cells.

But Also, Education

The Campaign for Science and Engineering's Sarah Main writes at the Guardian that increased R&D spending should also come with investment in education.

Pages

At the Guardian, the University of Edinburgh's Nikolay Ogryzko argues that universities need to better invest in postdocs' careers.

Researchers who go persevere after an early funding setback end up with more highly cited papers later on, according to the Economist.

Nature News reports that female scientists setting up their first labs tend to have lower salaries and smaller staffs than their male peers.

A new analysis by Northwestern University researchers finds that female and male first-time PIs receive differing amounts of funding.