The Scan

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.

Brewery Science

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Responsible Use

A bioethicist argues for the responsible use of germline gene editing.

This Week in Science

In Science this week: factors influencing retrotransposon integration sites, and more.

A peer reviewer's suggestion that a manuscript could be improved by the inclusion of male authors draws outrage on Twitter and elsewhere.

A new draft of the 21st Century Cures Act recommends additional funding for the US National Institutes of Health.

Just Getting Bigger

Luke Timmerman at Forbes speaks with Illumina's Jay Flatley about the DNA sequencing market.

This Week in Nature

In Nature this week: improved genome inference using population reference graph, and more.

While personalized medicine may show promise for treating patients, the cost of such treatments is a concern, the New York Times writes.

Corporate wellness programs may soon include genetic testing, the AP reports.

And Sounded

Protein & Cell says it published the human germline editing paper as a "sounding of an alarm."

In Genome Research this week: exome sequencing of mouse disease model strains, high-quality genomes of Saccharomyces cerevisiae strains, and more.

The UW's Wylie Burke and Dartmouth's Gilbert Welch argue that whole-genome testing may do more harm than good, and a related poll.

Stanford University researchers are studying top athletes to uncover genes linked to performance.

This Week in PNAS

In PNAS this week: epigenetic changes linked with high-altitude pulmonary edema, transcriptome profiling of maize leaf development, and more.

Funds Needed

A report from MIT identifies areas of scientific research where declining research support is hindering needed advances.

A retrovirus that's been integrated into the human genome appears to have a role in embryonic development, researchers report.

Differences in DNA methylation could be used to distinguish between DNA samples obtained from identical twins, researchers say.

This Week in PLOS

In PLOS this week: phylogenetic study of hepatitis E viruses in Swedish moose, recombination sites in the honeybee genome, and more.

A Few Snags

An Australian study of personalized medicine has run into problems as it recruits patients.

Industrial Focus

The proposed Canadian budget emphasizes partnerships with industry, Nature News reports.

The University of Arizona's Raina Maier writes that an understanding of the Earth's microbiome is needed.

This Week in Science

In Science this week: mtDNA analysis give glimpse into decline of Neanderthals in Europe, and more.

Many researchers call the work by Chinese scientists, who used the gene editing technology on human germlines, unethical, among other things. 

At Technology Review, University of California,Berkeley's Jennifer Doudna discusses the power, and possible perils, of genome editing.


The US Department of Defense plans to begin collecting data so that it can determine whether women face discrimination when seeking grants from the agency.

Foundations that offer research grants often have requirements for submitting progress reports that need to be followed.

A study appearing in the Proceedings of the National Academy of Sciences reports women are now preferentially chosen over men for tenure-track positions in STEM.

As researchers spend more time in postdoc positions, others look for ways to change the system.