The Scan

To find better treatments for depression, the Broad Institute's Steven Hyman says a large-scale genetic study of the condition is needed.

Researchers link mitochondrial dysfunction to glaucoma.

Researchers scour the genomes of supercentenarians, looking for a clue to long life, but come up short.

This Week in Nature

In Nature this week: variant linked to reduced typhoid fever risk, and more.

With Your Mind!

Researchers have coupled optogenetics with cybernetics to control gene expression using brain waves.

Contamination may be affecting a number of microbiome studies, according to a new paper out in BMC Biology.

BioRxiv Turns One

The creators of BioRxiv say the preprint server is off to a good start.

In Genome Research this week: genomic characterization of E. coli found outside the intestines, single haplotype human genome assembly, and more.

This Week in PNAS

In PNAS this week: cat domestication signatures, transcriptional artifacts linked to blood sample storage, and more.

The Look of It

Co.Design says Fluidigm's Juno system looks likes a cross between a Jawbone speaker and a 1980s Macintosh.

An Australian research team describes the life cycle of neochromosomes.

To the Neuron

A combination of genomic analysis and iPS cell-based studies homed in on a possible cause of a boy's autism.

Star-studded Prize

Jennifer Doudna, Emmanuelle Charpentier, Victor Ambros, and Gary Ruvkun are among the winners of the Breakthrough prize.

Dan Koboldt at MassGenomics discusses the challenges of more extensive whole-genome sequencing.

Organizing It All

Decode is using a genomically ordered relations database to handle its data, IEEE Spectrum says.

This Week in PLOS

In PLOS this week: rhythms in DNA methylation patterns, Jerusalem artichoke transcriptome, and more.

The Human Protein Atlas finds that the tissue in the human body harboring the highest number of unique proteins is the testis.

Google is offering genome data storage and analysis, Tech Review says.

Change Afoot?

The Chinese government plans to change how it awards research grants.

This Week in Science

In Science this week: genome of an ancient European Russian man, and more.

Journal editors and others have developed a set of guidelines for reporting preclinical research to help address the issue of reproducibility.

And Covered

Google is to cover cancer genome testing for employees beginning in 2015.

With the coming change in party in control of the US Senate, the heads of committees overseeing science policy and funding will also change.

This Week in Nature

In Nature this week: golden snub-nosed monkey genome, and more.

Changes to Gut Bugs

A new study finds that the human gut microbiome diverged rapidly from the ape microbiome.


Graduate students in India are protesting their low pay.

A study of hiring patterns appearing in Science Advances finds that institutional prestige of where someone got their PhD affects where they land a faculty position.

Twitter may not just be a land of over-sharing and self-promotion, but also a place to grow scientific contacts and possibly land a job, Nature reports.

The US National Institutes of Health is seeking thoughts on the development of an emeritus award for senior researchers.