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The Year's Best

More than half of the items on the Scientist's list of top innovations of the past year are genomics-related.

The top spot went to Edico Genomics' Dragen Bio-IT processor. This device aims to speed up the time it takes to analyze a genome and scale down the hardware needed to the size of chip that can be installed into a desktop-sized server. According to Edico, a genome that would typically take 24 hours to analyze would take 18 minutes with Dragen.

"This looks to be a promising solution for processing data efficiently and quickly," Tara Rock, the manager of New York University's genomics core facility, tells the Scientist.

Just behind Edico Genomics are two Illumina products — MiSeqDx and HiSeq X Ten — followed by BioNano Genomics' IrysChip V2.

To develop its list of top life science products from 2014, the Scientist turned to a panel of five judges — Rock, Thomson Reuters' Miriam Bayes, Eric Schadt from the Icahn School of Medicine at Mount Sinai, Domain Associates' Kim Kamdar, and David Ecker, the cofounder of Isis Pharmaceuticals and founder of Ibis Biosciences.

The Scan

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.

Study Examines Relationship Between Cellular Metabolism, DNA Damage Repair

A new study in Molecular Systems Biology finds that an antioxidant enzyme shifts from mitochondria to the nucleus as part of the DNA damage response.

Stem Cell Systems Target Metastatic Melanoma in Mouse Model

Researchers in Science Translational Medicine describe a pair of stem cell systems aimed at boosting immune responses against metastatic melanoma in the brain.

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.