President Obama will leave office in less than six months, so Nature News has set out to explore what kind of legacy he leaves behind for such issues as climate change, biomedicine, scientific integrity, space research, and more.

Early in his administration, Obama overturned restrictions on research using embryonic stem cells and later launched initiatives to map the brain and cure cancer.

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A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.

NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.

In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.