This Week in Science

In this week's Science, an international group of researchers publishes a report of genetic mutation signatures associated with tobacco smoke. They analyzed the genomes of 5,000 tumors from smokers and non-smokers, representing 17 different cancers for which smoking is a risk factor. From this, they discovered a complex series of mutations associated with smoke exposure.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.