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This Week in Science: Sep 23, 2016

In Science this week, an international team of scientists present a global genetic interaction map for Saccharomyces cerevisiae, identifying nearly one million interactions between 90 percent of the yeast's essential and non-essential genes. They specifically found about 550,000 negative mutations and about 350,000 positive mutations, which helped them uncover the yeast's essential genes, map out general regulatory connections between genes, and gain insights into functionally related genes.

And in Science Translational Medicine, two King's College London researchers discuss the progress made in genomics, precision medicine, and new drugs and diagnostics following years of investments into translational research made by the UK's National Institute for Health Research. They also highlight the need for experimental efficiency going forward to minimize the time between laboratory work and clinical application, while maintaining safety standards for patients.