This Week in Science

In Science this week, a multi-institute team of investigators reports on their efforts to replace multiple codons genome-wide in the bacteria E. coli. The researchers aimed to reduce the number of codons in the E. coli genome to 57 from 64, and replaced more than 60,000 instances of seven codons with synonymous alternatives across all protein-coding genes.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.