This Week in Science

In this week's Science, a team of Japanese scientists reports a modified version of the genome-editing technology CRISPR that can perform DNA substitutions without cleaving DNA. CRISPR functions by inducing double-strand DNA breaks followed by DNA repair. However, this process can result in unwanted genetic insertions and deletions in genomic DNA.

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.