This Week in Science | GenomeWeb

This Week in Science

In Science this week, a group of Stanford University researchers present data pointing to an unexpectedly important role for RNA splicing in modulating phenotypic traits. In their study, the researchers quantified the contribution of cis-acting genetic effects at all major stages of gene regulation from chromatin to proteins, finding that splicing quantitative trait loci are "major contributors to complex traits," on par with variants that affect gene expression levels.

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