This Week in Science: Jan 15, 2016

Jan 15, 2016

In this week's Science, a team led by University of California, Berkeley, researchers presents new details about how the genome-editing technology CRISPR/Cas9 identifies and positions its target DNA. In the CRISPR process, the enzyme Cas9 is directed to its target by an RNA-DNA hybrid helix in an R-loop formation.

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The Scan

Preprints During Lockdown

New analyses indicate female researchers are publishing less during the coronavirus pandemic than male researchers, according to Nature News.

ApoE and COVID-19

A study suggests people with the ApoE e4 genotype may be more likely to have severe COVID-19 than those with other genotypes, the Guardian says.

Search for Genetic Clues to COVID-19 Severity

Direct-to-consumer genetic testing companies are searching for a genetic reason for why some people, but not others, become gravely ill with COVID-19, the Detroit Free Press reports.

PNAS Papers on Retinal Development, Adoptive T Cell Transfer, Blood Cell Differentiation

In PNAS this week: forward genetics-base analysis of retinal development, interactions of T cell receptors with neoantigens in colorectal cancer, and more.

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