This Week in Science

In Science Translational Medicine, a multi-institute team of scientists presents data explaining why a promising HIV vaccine could produce conflicting results — protecting some patients from infection, but increasing risk in others. The study found that the vaccine only offered protection in those with a specific variant in their human leukocyte antigen (HLA) gene, which helps regulate antibody production.

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Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.