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In Science this week, two research groups report data suggesting that cytosine base editors can trigger a significant number of off-target mutations. In the first paper, a group of US and Chinese scientists developed a method for detecting off-target mutations in mouse embryos following editing by either CRISPR-Cas9 or adenine or cytosine base editors.

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A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.

LiveScience reports that a novel mutation in the LPL gene was uncovered in three siblings with very high triglyceride levels.

The president of Nankai University is embroiled in a data manipulation scandal, the South China Morning Post reports.

In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.