This Week in Science

In Science Advances this week, a team of US and Chinese collaborators publish a study shedding light on the transcriptional regulation of the inflammasome NLRP3, which is hyperactivated in a number of inflammatory syndromes including multiple sclerosis and cardiovascular disorders. They show that the B7 family-related protein VSIG4 suppresses the expression of NLRP3, as well as interleukin 1-beta, in macrophages during the inflammatory response in vitro and in vivo.

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Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.