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In this week's Science, a team of US and Japanese investigators publish a study showing that protein destabilizing mutations encoding nongenetic variation can drive evolutionary innovation, shedding new light on a disputed theory. While natural selection can explain adaptation, it is unable to account for how mutations encode new function.

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Politico notes that the Biden Administration has not yet nominated a permanent Food and Drug Administration commissioner. 

Anthony Fauci also informed the World Health Organization executive board that the US would be joining the COVAX initiative, according to CNBC.

A new preprint suggests some SARS-CoV-2 variants could affect the effectiveness of current vaccines, the Associated Press reports.

In Nature this week: Australian lungfish provides details on the movement of vertebrate life from water to land, and more.