This Week in Science

In Science this week, an international team reports analyzing DNA of ancient humans from Northern Africa, revealing a lack of relatedness to ancient Europeans that counters the hypotheses of gene flow from Paleolithic Europeans into Late Pleistocene North Africans. The researchers sequenced DNA extracted from the bone matter of several 15,000-year-old individuals who lived in what is now Morocco, and compared their results to genomic data on other ancient and modern individuals.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.