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In Science this week, two groups publish studies offering clues about the genetics behind cancer susceptibility to immune checkpoint inhibition. In the first, researchers used CRISPR screening on a mouse melanoma cell line resistant to immune checkpoint inhibitors to identify several genes whose inactivation enhanced tumor sensitivity to such drugs, including three — Pbrm1, Arid2, and Brd7 — that produce proteins part of a chromatin remodeling complex.

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A New Zealand minister says the country's genetic modification laws need to be re-examined to help combat climate change, the New Zealand Herald reports.

A new analysis finds some cancers receive more nonprofit dollars than others.

An Australian mother's conviction in the deaths of her children may be re-examined after finding that two of the children carried a cardiac arrhythmia-linked gene variant.

In Science this week: comparative analysis of sex differences in mammal gene expression, and more.