This Week in Science

In Science this week, the University of California, Berkeley's Jennifer Douda and colleagues report the crystal structures of two Cas enzymes involved in CRISPR genome editing, as well as cryo-electron microscopy structure of the full CRISPR locus integration complex, providing new insights into how components of the system interact with one another as a viral defense mechanism for bacteria.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.