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In Science this week, the University of California, Berkeley's Jennifer Douda and colleagues report the crystal structures of two Cas enzymes involved in CRISPR genome editing, as well as cryo-electron microscopy structure of the full CRISPR locus integration complex, providing new insights into how components of the system interact with one another as a viral defense mechanism for bacteria.

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A genetic genealogy analysis helped secure the release of a California man from prison after getting his murder conviction overturned, the Guardian reports.

Technology Review discusses the concerns that come along with the ability to quickly synthesize viruses like SARS-CoV-2.

Researchers have uncovered large bacteriophages whose genomes include translational machinery, Live Science reports.

In PNAS this week: role for Myc in alternative splicing regulation in prostate cancer, variation in methylation in Arabidopsis, and more.