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In Science this week, the University of California, Berkeley's Jennifer Douda and colleagues report the crystal structures of two Cas enzymes involved in CRISPR genome editing, as well as cryo-electron microscopy structure of the full CRISPR locus integration complex, providing new insights into how components of the system interact with one another as a viral defense mechanism for bacteria.

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Time magazine looks into how liquid biopsies are changing cancer care.

In PNAS this week: similar muscle protein patterns across hypertrophic cardiomyopathy phenotypes, analysis of gene expression and brain anatomy in major depression, and more.

The Lancet has made changes to its peer-review process in response to its recent retraction of a COVID-19-related paper, Science reports.

The New York Times reports that a series of emails show how Department of Health and Human Services officials sought to silence the Centers for Disease Control and Prevention.