This Week in Science

In Science this week, a multi-institute research team reports a study establishing that tumors with defects in a genome maintenance pathway called mismatch repair (MMR) are highly responsive to a certain type of immunotherapy. Building off of a previous study that showed colorectal cancers with MMR deficiency were sensitive to immune checkpoint blockade with anti-PD-1 antibodies, the scientists analyzed 86 patients with 12 different MMR-deficient tumor types in an ongoing clinical trial.

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The ancestors of the Arizona bark scorpion and other scorpions and spiders underwent whole-genome duplication, KJZZ reports.

A cryptographic approach could help researchers keep genomic data private while researchers analyze it, Scientific American reports.

Andy Page, the former president of 23andMe, has joined a diabetes-management startup, according to CNBC.

In Cell this week: regulatory changes in pancreatic cancer, metabolic shifts in Alzheimer's disease, and more.