This Week in Science

A team from Brandeis University reports in Science this week on the discovery of a handful of ancient genetic mutations that are responsible for the activity of the cancer drug Gleevec against tumors expressing one type of oncogene, but not a related one. Gleevec works by blocking the activity of Abl tyrosine kinase, but is ineffective against closely homologous tyrosine kinases such as Src.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.