This Week in Science

In this week's Science, a team of researchers from industry and academia report on how the deletion of a single microRNA from pluripotent stem cells enabled them to form both embryonic and non-embryonic lineages, revealing a role for the small, non-coding RNAs in regulating pluripotency. Specifically, when miR-34a was eliminated from embryonic stem cells, these engineered cells were able to generate both embryonic and extra-embryonic lineages.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.