This Week in PNAS

Researchers from Case Western Reserve University report in the early edition of the Proceedings of the National Academy of Sciences this week that they've uncovered mutations linked to colorectal cancer that seem to be specific to African-American patients. The investigators performed exome sequencing on a discovery set of 31 African-American patients with colorectal cancer.

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An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.