This Week in PNAS

Researchers from the Fred Hutchinson Cancer Research Center and elsewhere report on molecular subgroups detected in human glioma samples that were analyzed using a combination of genomic data. The team used multidimensional scaling to assess single nucleotide changes, copy number alterations, transcriptome patterns, and methylation profiles generated by the Cancer Genome Atlas on glioblastoma and low-grade glioma tumors.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.