This Week in PNAS

In a study slated to appear online this week in the Proceedings of the National Academy of Sciences, researchers from Yale University and elsewhere describe findings from an effort to identify characteristic genomic features of clear cell renal cell carcinoma (ccRCC), a kidney cancer that may have sarcoma-like histological features. The team did exome sequencing on carcinomatous tumor, sarcomatoid tumor, and matched normal samples from 21 individuals who had ccRCC showing signs of sarcomatoid transformation.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.