This Week in PNAS

The Max Planck Institute of Evolutionary Anthropology's Svante Pääbo and colleagues present findings from an effort to sequence DNA from two new Denisovan individuals whose ancient tooth samples were found in the same Altai mountain cave where the original Denisovan finger was discovered. The team successfully generated nuclear DNA sequences for an individual believed to be more than 50,000 years old whose mitochondrial DNA was sequenced previously.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.