This Week in PNAS

In a study appearing online this week in the Proceedings of the National Academy of Sciences, researchers from the US and Brazil demonstrate the feasibility of finding cell-free DNA in the cerebrospinal fluid that stems from tumors in the brain or spinal cord. The team started by using targeted sequencing and/or exome sequencing to find cancer-specific mutations in tumor samples from 35 individuals with primary gliomas or medulloblastomas.

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Jay Shendure and his colleagues have developed a new method to more comprehensively identify human cell types, the NY Times reports.

Researchers in the UK and Japan have shown that infertility in mice with three sex chromosomes can be overcome, according to the Guardian.

China is embracing preimplantation genetic diagnosis, Nature News reports. 

In PLOS this week: host genetic factors associated with cervical neoplasia progression, population patterns for an ancient flowering rainforest plant, and more.