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This Week in PNAS

Researchers from China and the US explore and edit epigenetic patterns in individual mammalian egg cells from mouse models. Using single-cell bisulfite sequencing, the team demonstrated that cytosine methylation patterns in first polar body cells (PB1) can be used to assess methylation patterns in corresponding single cells, before going on to edit methylation marks related to mouse coat color or methylation marks related to familial Angelman syndrome in humans.

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According to New Scientist, GEDmatch changed its terms and conditions over the weekend to opt its users out of law enforcement searches.

The Atlantic looks into time spent pursuing gene leads generated through candidate gene studies.

A twin study uncovers evidence that genes may influence whether someone gets a dog, Martha Stewart reports.

In PNAS this week: Cdx2 cells can help regenerate heart tissue in mice following a heart attack, PIWI-interacting small RNA levels in human cancer, and more.