This Week in PNAS

In a study appearing in the early, online edition of the Proceedings of the National Academy of Sciences, Texas-based researchers used a combination of gene expression data, DNA methylation profiles, and methyl-CpG binding protein 2 interaction patterns to study Rett syndrome in a mouse model of the disease. Results from the analysis suggest that MeCP2 not only binds to methylated cytosine bases that neighbor guanine, but also to cytosines that are methylated in a non-CG context.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

The Jackson Laboratory has filed a complaint accusing Nanjing University of breeding and re-selling its mouse models, the Hartford Courant reports.

Oxford researchers are turning to virtual reality to visualize genes and regulatory elements, Phys.org says.

In Science this week: neutrophils rely on microRNA to protect against lung inflammation, and more.

China is moving forward with plans to sequence a million citizens, the Wall Street Journal reports.