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A University of Utah team takes a look at the impact that DNA architecture has on CRISPR-Cas9-based genome editing in vivo in the budding yeast model organism Saccharomyces cerevisiae. Using two S. cerevisiae sequences with distinct promoter and nucleosome occupancy patterns, the team tracked the cleavage wherewithal of a commonly used Cas9 nuclease originating in the bacterial species Streptococcus pyogenes.

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Russian CRISPR researcher moves along with plans to ultimately alter the genes of embryos of deaf couples, though awaits regulatory approval, Nature News reports.

University of California, San Francisco, researchers have uncovered a gene mutations that appears to make a father-son duo more efficient sleepers.

NPR reports a large health insurer has begun to cover some pharmacogenetic tests for psychiatric drugs.

In PLOS this week: genome-wide association study of non-syndromic orofacial cleft subtypes, epigenetic and transcriptomic analysis of pancreatic ductal adenocarcinoma, and more.