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A University of Utah team takes a look at the impact that DNA architecture has on CRISPR-Cas9-based genome editing in vivo in the budding yeast model organism Saccharomyces cerevisiae. Using two S. cerevisiae sequences with distinct promoter and nucleosome occupancy patterns, the team tracked the cleavage wherewithal of a commonly used Cas9 nuclease originating in the bacterial species Streptococcus pyogenes.

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A Harvard University professor has been charged with making false claims regarding funds he received from China, the New York Times reports.

Discover magazine reports that animal dissections might dissuade students from science careers, but that a firm has developed synthetic frogs for dissections.

Nature News reports that a US panel is reviewing current guidelines for federally funded gain-of-function viral research.

In PNAS this week: de novo mutation patterns among the Amish, an alternative RNA-seq method, and more.