This Week in PNAS

A University of Pennsylvania-led team reports the Proceedings of the National Academy of Sciences this week that it developed a potential gene therapy for retinitis pigmentosa. The condition has been linked to more than a hundred different mutations in the rhodopsin gene, RHO. The research team combined an shRNA that targets RHO, independent of mutations in it, with a RHO replacement cDNA that is resistant to RNA interference on a single adeno-associated viral vector.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.