This Week in PNAS

In the early, online version of the Proceedings of the National Academy of Sciences, a Massachusetts General Hospital- and Massachusetts Institute of Technology-led team describes a strategy for targeting recurrent mutations in the isocitrate dehydrogenase enzyme-coding genes IDH1 and IDH2 in lower-grade glioma central nervous system tumors.

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An analysis of UK Biobank data finds hemochromatosis to be more prevalent than thought, according to the BBC.

An analysis finds that female biomedical researchers receive fewer prizes than male ones, and when they do win prizes, they are less prestigious.

In Nature this week: improved genomic analysis using a graph genome reference, tumor mutational burden could predict clinical response to immune checkpoint inhibitors, and more.

Federal researchers tell the Los Angeles Times that the shutdown is causing missed research opportunities as they try to keep their experiments going.