This Week in PNAS

A University of Oxford-led team takes a look at the relationship between genotype and insecticide resistance phenotypes in the Anopheles gambiae mosquito as part of a broader study quantifying insecticide resistance patterns in the African malaria vector. The researchers sampled An. gambiae from nearly 1,200 sites in Africa, profiling insecticide resistance and using a geostatistical modeling approach to consider co-variation in resistance to multiple insecticides.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.