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In the early, online edition of Proceedings of the National Academy of Sciences, investigators from the University of Massachusetts and Tufts University demonstrate the feasibility of establishing a mouse model of genetically-induced emphysema using CRISPR/Cas9-based editing to lop out half a dozen paralogs of Serpina1 — a gene implicated in alpha-1 antitrypsin deficiency (AAT)-related forms of emphysema in humans.

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A new analysis founds that nearly half the late-stage clinical trials sponsored by a US National Cancer Institute program influence patient care.

Technology Review reports that sickle cell patients are optimistic about gene editing to treat their disease, but are worried about how available it will be.

The owner of the GEDmatch website tells CBS12 he is considering charging law enforcement a fee to use the site.

In Nature this week: babies born by caesarean section are more likely to have altered gut microbiota profiles, and more.