This Week in PNAS

In the Proceedings of the National Academy of Sciences, researchers from the US and Finland explore the role that amplifications of the oncogene Akt3 play in the progression of the brain cancer glioma. After detecting amplifications of Akt3, Akt2, and Akt1 in several cancer types — including the most common form of glioma, called glioblastoma — the researchers tracked glioma progression and gene expression profiles in mouse models of glioma that harbored various Akt isoforms.

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Five researchers are to share this year's Albany Medical Center Prize for their work on the CRISPR/Cas9 gene-editing tool, the AP reports.

Stat News reports on how white supremacists cope with surprising genetic ancestry testing results.

In Genome Research this week: sex-biased gene expression evolution in malaria mosquitos, method to find ancient selective sweeps, and more.

Iceland has nearly eliminated Down syndrome from its population, CBS News reports.