This Week in PNAS

In the Proceedings of the National Academy of Sciences, researchers from the US and Finland explore the role that amplifications of the oncogene Akt3 play in the progression of the brain cancer glioma. After detecting amplifications of Akt3, Akt2, and Akt1 in several cancer types — including the most common form of glioma, called glioblastoma — the researchers tracked glioma progression and gene expression profiles in mouse models of glioma that harbored various Akt isoforms.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.