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Steve Carr's group has used quantitative proteomics (SILAC) and affinity enrichment to provide "unbiased, robust and comprehensive identification" of the proteins that bind to small-molecule probes and drugs. They say the method is scalable and general and, in this paper, apply it to identify targets of kinase inhibitors and immunophilin binders.

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SARS-CoV-2 vaccine developers are evaluating further vaccine doses as well as modified doses to keep up with new viral variants, according to CNN.

The New York Times reports that a new viral variant of concern has been identified in New York City.

In Nature this week: spatiotemporally resolved map of the human cell cycle, folding single-cell RNA sequencing into cancer drug studies, and more.

CNN reports that a US Food and Drug Administration document says Johnson & Johnson's SARS-CoV-2 vaccine meets the requirements to receive an Emergency Use Authorization.