This Week in PNAS

Steve Carr's group has used quantitative proteomics (SILAC) and affinity enrichment to provide "unbiased, robust and comprehensive identification" of the proteins that bind to small-molecule probes and drugs. They say the method is scalable and general and, in this paper, apply it to identify targets of kinase inhibitors and immunophilin binders.

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A new analysis examines the gender gap among paper authors in the sciences and says it may take decades or more to close.

Researchers have uncovered signals of selection that may enable the Bajau people to free five hundreds of feet deep, Reuters reports.

In Science this week: paternally inherited cis-regulatory structural variants in autism, and more.

A new report outlines issues facing the implementation of personalized medicine in the UK, the Independent reports.