This Week in PLOS

In PLOS Genetics, researchers from Canada, Germany, and the US describe a potential role for Notch signaling family genes in congenital heart disease. The team used a combination of exome sequencing and targeted sequencing to assess 106 affected individuals and 76 unaffected individuals from 51 French Canadian families in which left-ventricular outflow tract obstructions, a diverse set of developmental heart conditions, occurs.

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.