This Week in PLOS

In PLOS Genetics, researchers from Canada, Germany, and the US describe a potential role for Notch signaling family genes in congenital heart disease. The team used a combination of exome sequencing and targeted sequencing to assess 106 affected individuals and 76 unaffected individuals from 51 French Canadian families in which left-ventricular outflow tract obstructions, a diverse set of developmental heart conditions, occurs.

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The apple has traveled westward and eastward along the Silk Road, according to a new genetic analysis.

In Nature this week: GWAS data used to reposition drugs for psychiatric use, and more.

Genetic disease risk information doesn't always spur people to make healthy lifestyle changes, according to the Associated Press.

A University of California, San Diego-led team has used liquid biopsies to uncover possible treatments for patients with cancers of unknown primary.