This Week in PLOS

In PLOS One, Japanese researchers describe germline variants in new and known prostate cancer risk genes in the Japanese population. The team did exome sequencing on 140 individuals with prostate cancer from 66 families, uncovering an association between the prostate cancer and germline variants in genes already implicated in the disease, such as BRCA2 and HOXB13.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.