This Week in PLOS

In PLOS Pathogens, researchers from the US, Sweden, and Denmark describe genetic and other host factors influencing susceptibility to necrotizing soft tissue infections caused by invasive group A Streptococcus in mice. The team used a forward systems genetics approach to screen recombinant inbred mouse strains with varying susceptibility to group A Streptococcus infection.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.