This Week in PLOS

Mutations in the RNA-splicing gene SRSF1 prompt the progression of some small-cell lung cancer cases in individuals of Chinese ancestry, according to a PLOS Genetics study. When they sequenced the protein-coding and transcriptome sequences of primary tumors from 99 individuals with small-cell lung cancer, researchers from China and the US saw altered regulation and/or mutations of known tumor suppressor gene such as TP53 and RB1 in the majority of cases.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.