This Week in PLOS

In PLOS Genetics, a Stanford University-led team describes de novo and rare variants it identified in an exome sequence-based study of individuals with congenital heart disease. The researchers began by profiling protein-coding sequences in 59 individuals with rare, non-syndromic heart malformations called atrioventricular septal defects, their unaffected parents, and 59 unaffected control trios.

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Oxford Nanopore Technologies is looking into dual listings in London and Hong Kong, according to the South China Morning Post.

The New York Times looks into medical research funding in the US and how the grant system might not be funding the best work.

US lawmakers proposed increasing the National Science Foundation budget, including its facilities account, Science reports.

In PNAS this week: effects of gene deletions on bacterial metabolic networks, genetic responses to sea star wasting disease, and more.