This Week in PLOS

In PLOS Genetics, researchers from China and the US describe a variant in the MAP kinase family gene MKK7 that appears to help in predicting lung cancer risk and patient outcomes in individuals from the Chinese population. The team investigated potential lung cancer associations for a handful of rare variants identified in a retrospective study of more than 5,000 Chinese individuals with the disease and nearly 5,200 without.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.