This Week in PLOS

Researchers from the Netherlands report in PLOS Computational Biology this week on their Bayesian-based approach that uncovered novel RIG-I-like receptor (RLR) regulators. The RLR pathway, they note, helps identify cytosolic viral DNA, which then sets off type I interferon production and the innate immune response.

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The apple has traveled westward and eastward along the Silk Road, according to a new genetic analysis.

In Nature this week: GWAS data used to reposition drugs for psychiatric use, and more.

Genetic disease risk information doesn't always spur people to make healthy lifestyle changes, according to the Associated Press.

A University of California, San Diego-led team has used liquid biopsies to uncover possible treatments for patients with cancers of unknown primary.