This Week in PLOS

In PLOS One, a Washington University School of Medicine team describes a missense variant that appears to contribute to an autosomal dominant form of primary open-angle glaucoma that begins manifesting itself in adulthood. The researchers did exome sequencing and linkage analyses on members of a large, multi-generation African-American family affected by the progressive eye disease, uncovering a glaucoma-associated missense variant in a fibulin family gene called EFEMP1.

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A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.