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Researchers from France and Denmark describe mitochondrial DNA patterns detected in ancient bone samples from the extinct steppe bison, Bison priscus, in PLOS One. Using a combination of Illumina sequencing, Sanger sequencing, and PCR amplification on DNA from a 19,000-year-old rib bone sample, the team put together a complete mitochondrial genome sequence for the steppe bison, covered to an average depth of more than 10-fold.

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