This Week in PLOS

In PLOS One, researchers from India used comparative genomics on sequences from clinical isolates of Mycobacterium tuberculosis to put together a pangenome for the tuberculosis-causing bug. The team considered genomes from 96 M. tuberculosis complex strains for its analysis — a set that included assemblies for eight newly sequenced clinical isolates from India.

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In an against-all-odds twist, a researcher studying exceeding rare FOXG1 mutations discovers her daughter has the syndrome.

An effort by Genomics Medicine Ireland is creating a database of diseases based on the genomics of people in Ireland. It now is looking into the possibility of including Scotland in its work.

In recent weeks, the direct-to-consumer genetics firm has rolled out a health hub where customers can share information concerning 18 common health conditions.

In PLOS this week, new genes associated with prostate cancer risk, genetic patterns in M. bovis, and more.