This Week in PLOS

In PLOS Genetics, researchers from the University of Bonn and elsewhere describe chromosome 5 variants behind a urinary/rectal malformation condition called classic bladder exstrophy, which occurs due to glitches during embryonic development. The team tracked down the SNPs through a GWAS involving 110 individuals of European ancestry with the condition and nearly 1,200 without.

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A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.