This Week in PLoS

Jan Felix Drexler and his colleagues report that the 3'-X-tail element of the hepatitis C virus is highly conserved. By de novo sequencing, they characterized the tail and then they developed a prototype RT-PCR assay test to determine if this region could be used as a diagnostic target. The authors say the test was robust against genotype variation and precise in determining virus quantification.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.