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This Week in PLOS

In PLOS Genetics, a Columbia University-led team searches for rare variants contributing to a severe condition called congenital diaphragmatic hernia (CDH), uncovering damaging de novo mutations in the transcription factor-coding gene MYRF. Using new and previously sequenced exomes for 362 affected children and their unaffected parents, the researchers saw de novo coding mutations in MYRF in four CDH cases.

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Australia will not be regulating gene editing of plants, animals, and human cell lines as long as no new genetic material is incorporated, reports Nature News.

The Washington Post reports that the US Department of Agriculture told its researchers to label peer-reviewed articles as "preliminary" work.

Researchers have sequenced the genomes of both the coast redwood and the giant sequoia, according to the San Francisco Chronicle.

In PNAS this week: study of epigenetic patterns in mammalian eggs, clonal expansion patterns in CD8+ T cells, and more.