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This Week in PLOS

In PLOS Genetics, a Fred Hutchinson Cancer Research Center-led team shares a statistical approach for finding somatic mutation-based associations. In addition to taking uncertainty around somatic mutation calling into consideration, they say, the so-called "Somatic mutation association test with measurement errors," or SAME, approach reveals associations involving specific mutations or oft-mutated genes.

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The American Prospect writes that the pilot program to test the DNA of migrants could lead to more family separations.

An international commission is to develop a report on how researchers, clinicians, and regulators should evaluate the clinical applications of human germline genome editing.

The US Department of Agriculture presents a new blueprint for animal genomic research.

In Genome Research this week: repetitive element deletion linked to altered methylation and more in form of muscular dystrophy; human contamination in draft bacterial and archaeal genomes; and more.